In this episode of the Huberman Lab podcast, Dr. Layne Norton, an expert in nutrition and fitness, discusses various health and nutrition topics with host Andrew Huberman. The discussion examines scientific evidence related to fat loss, muscle strength, hypertrophy, and metabolism, deliberating on dietary strategies like protein intake distribution and carbohydrate timing. It also covers the impact of supplements and pharmaceuticals such as GLP-1 agonists on appetite and metabolic health. Dr. Norton emphasizes the importance of scrutinizing evidence hierarchy, focusing on practical outcomes, and recognizing individual variability in response to dietary and fitness plans. The episode provides insights into optimizing health outcomes through personalized nutrition and fitness strategies, especially for those over 50.